Sugar acids and derivatives
TARGETMOL CHEMICALS INC D-AP5 10MG
Also available in 1 mL, 1 mg, 2 mg, 5 mg, 25 mg, 50 mg and bulk. Please contact Fisher for quotes. D-AP5 (D-APV) is an NMDA receptor antagonist. Purity 100%
Apexbio Technology LLC Heparin(Synonyms: Heparin Sodium, Unfractionated Heparin, Sodium Heparin, Heparinic Acid, Liquaemin, Calciparine), 500mg, CAS: 9005-49-6.
Heparin (CAS 9005-49-6) is a highly sulfated glycosaminoglycan known primarily for its anticoagulant properties In biological systems it is stored in granules within specific animal tissues and cells potentially serving defensive roles against pathogens In vitro studies demonstrate that Heparin dose-dependently suppresses granulocyte aggregation and degranulation triggered by FMLP or serum-activated zymosan and specifically blocks FMLP-induced superoxide anion production Additionally in rat models Heparin treatment reduces both the binding affinity and density of angiotensin II receptors on adrenal cells resulting in decreased angiotensin II-stimulated aldosterone secretion Heparin is extensively applied in biomedical research to investigate granulocyte-mediated inflammation and renin-angiotensin system signaling
Apexbio Technology LLC HyperTrap Heparin HP Column(Synonyms: Heparin Affinity Column, Heparin HP Column, HyperTrap Heparin Affinity Chromatography Column), 1ml.
HyperTrap Heparin HP Column features the HyperChrom Heparin HP Agarose affinity chromatography resin which consists of heparin covalently immobilized on an agarose matrix Heparin is a naturally occurring glycosaminoglycan known for specific affinity interactions with various biomolecules including coagulation factors growth factors interferons lipoprotein lipase nucleic acid-binding proteins steroid receptors and antithrombin III This column enables efficient separation and purification of these proteins making it suitable for biochemical research proteomics analyses and protein characterization studies
Medchemexpress LLC Ethyl glucuronide-d5 | 1135070-98-2 | 97.6% | 227.22 | 1 MG
Ethyl glucuronide-d5 is a deuterium labeled Ethyl glucuronide. It is an endogenous metabolite of ethanol and serves as a biomarker for ethanol exposure, accumulating in hair to reflect alcohol intake over time. It is also an agonist for TLR4. This product is for research use only.
- Deuterium labeled compound
- Stable heavy isotope
- Tracer for quantitation during drug development
- Internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Used as a tracer
- Can be used as an internal standard for quantitative analysis
- Potential to affect the pharmacokinetic and metabolic profiles of drugs (due to deuteration)
Medchemexpress LLC Ethyl glucuronide | 17685-04-0 | 99.2% | 222.19 | 1 ML
Ethyl glucuronide is an endogenous metabolite of ethanol. It serves as a biomarker for ethanol exposure, accumulating in hair and reflecting alcohol intake over time. It is also an agonist for TLR4.
- Endogenous metabolite
- Biomarker for ethanol exposure
- Agonist for TLR4
- Appearance: Solid, white to off-white
- Storage: -20°C, protect from light, stored under nitrogen. In solvent: -80°C for 6 months; -20°C for 1 month (protect from light, stored under nitrogen).
- Useful in research for studying ethanol exposure and its effects
- Can be used to block the formation of the TLR4-MD2 complex and stimulate the expression of TLR4-dependent SEAP protein in HEK-TLR4 cells
- Has been shown to reduce tactile threshold and induce hyperalgesia in Sprague-Dawley rat models
Medchemexpress LLC Collagenase (type D, animal-free) | 9001-12-1 | 10 MG
Collagenase (Type D, animal-free) is an enzymatic preparation for tissue digestion and dissociation in research applications. It combines collagenase and secondary protease activities and exhibits higher activity than comparable Type A preparations.
- Animal-free enzyme preparation suitable for tissue dissociation.
- Contains collagenase and secondary protease activities; higher activity than type A.
- Available in multiple sizes, including a 10 mg quantity.
- CAS no. 9001-12-1.
- Appearance: off-white to light yellow solid.
- Solubility: ≥ 50 mg/mL in water (in vitro).
- Storage: follow the certificate of analysis for recommended conditions.
- For research use only; not for patient use.
TARGETMOL CHEMICALS INC BLEOMYCIN SULFATE 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Bleomycin Sulfate (Blenoxane) a glycopeptide antibiotic is an anticancer agent for squamous cell carcinomas (SCC). In UT-SCC-19A cells the IC50 of Bleomycin Sulfate is 4 nM. purity: 99%
Medchemexpress LLC 4-Methylumbelliferyl-α-D-Glucopyranoside | 17833-43-1 | 99.99% | 338.31 | 25 MG
4-Methylumbelliferyl-α-D-Glucopyranoside is a fluorescent substrate for α-glucosidase, which releases the fluorescent moiety 4-methylumbelliferyl (4-MU) upon cleavage. 4-MU exhibits pH-dependent fluorescence excitation activity, with excitation wavelengths of 320 nm at low pH (1.97-6.72) and 360 nm at high pH (7.12-10.3). The emission wavelength of 4-Methylumbelliferyl-α-D-Glucopyranoside increases with decreasing pH, ranging from 445-455 nm. This compound can be utilized as a biomarker for Fabry and Pompe diseases to quantify α-glucosidase activity in infant blood spot samples.
- Fluorescent substrate for α-glucosidase.
- Releases fluorescent moiety 4-methylumbelliferyl (4-MU) upon cleavage.
- 4-MU has pH-dependent fluorescence excitation activity.
- Can be used as a biomarker for Fabry and Pompe diseases.
- Quantifies α-glucosidase activity in infant blood spot samples.
Sigma Aldrich Fine Chemicals Biosciences 4 Methylumbelliferyl alpha5MG
4 Methylumbelliferyl alpha5MG
Medchemexpress LLC Odn D-SL03 (sodium) | 1198621-85-0 | 98.6% | 9345 (free acid) | 10 MG
ODN D-SL03 sodium is a C-class CpG oligodeoxynucleotide TLR9 agonist supplied as a solid for research use. It stimulates peripheral blood mononuclear cells (PBMCs) to produce interferon-α, activates human B cells, NK cells, and mononuclear cells, and modulates antigen-presentation markers. The oligonucleotide sequence is 5'-tcgcgaacgttcgccgcgttcgaacgcgg-3'.
- Stimulates PBMCs to produce high levels of IFN-α.
- Activates human B cells, NK cells, and mononuclear cells.
- Up-regulates CD80, CD86, and HLA-DR expression on immune cells.
- Sequence-defined oligonucleotide: 5'-tcgcgaacgttcgccgcgttcgaacgcgg-3'.
- High purity (98.6%) suitable for research applications.
- Supplied as a solid with recommended storage at -20°C; in solvent, -80°C up to 6 months.
- Available in small amounts appropriate for assays (e.g., 10 mg).
- For research use only.