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Filtered Search Results
Medchemexpress LLC Integrin alpha 8 bet 5ug
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Integrin -8/ -1 coordinates the recruitment of mesenchymal cells during renal organogenesis and recognizes RGD sequences in ligands such as TNC FN1 SPP1 TGFB1 TGFB3 and VTN It plays a role in multiple cellular interactions critical for organogenesis including NPNT as a functional ligand in nephrogenesis Integrin alpha 8 beta 1 Protein Human (HEK293 Flag His) is a recombinant protein dimer complex containing human-derived Integrin alpha 8 beta 1 protein expressed by HEK293 with C-10 His C-Flag labeled tag Integrin alpha 8 beta 1 Protein Human (HEK293 Flag His) has molecular weight of 85-140 kDa
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Medchemexpress LLC 2,4-D sodium | 2702-72-9 | ≥98.0% | 243.02 | 500 MG
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2,4-D sodium (2,4-Dichlorophenoxyacetate) is a selective herbicide effective against broad-leaved weeds. It functions by inducing apoptosis and inhibiting DNA and protein synthesis, thereby disrupting normal plant growth and development. In laboratory studies, it inhibits the viability of A549 and WI38 cells with IC50 values of 126 μM and 115 μM, respectively, and can induce apoptosis by influencing the cell cycle. In vivo studies have also shown toxic effects on the reproductive system of male rats, including reduced organ weights and sperm viability.
- Selective herbicide for broad-leaved weeds.
- Induces apoptosis and inhibits DNA and protein synthesis.
- Inhibits A549 and WI38 cell viability in vitro.
- Affects cell cycle and induces apoptosis.
- Causes reproductive toxicity in male rats.
- Reduces organ weights and sperm viability in vivo.
- Increases FSH and LH levels in vivo.
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Medchemexpress LLC 2H-1-Benzopyran-2-one, 7-[(4-O-β-D-glucopyranosyl-ẞ-D-glucopyranosyl)oxy]-4-methyl- | 72626-61-0 | MFCD00063279 | 99.4% | 500.45 | 25 MG
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4-Methylumbelliferyl β-D-cellobioside is a fluorescent dye and a substrate for cellulase. With a purity of 99.4%, this compound has a molecular weight of 500.45.
- Functions as a fluorescent dye
- Acts as a substrate for cellulase
- Purity: 99.4%
- Molecular weight: 500.45
- Stable as powder at -20°C for 3 years or 4°C for 2 years
- Stable in solvent at -80°C for 6 months or -20°C for 1 month
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Aobchem (2-Chloro-3-methoxyphenyl)(cyclopropyl)methanol | 95% | C11H13ClO2 | 1g
(2-Chloro-3-methoxyphenyl)(cyclopropyl)methanol | 95% | C11H13ClO2 | 1g
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Medchemexpress LLC Cathepsin D and E FRET Substrate acetate | 99.8% | 1816.15 | 25 MG
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Cathepsin D and E FRET Substrate acetate is a fluorogenic substrate specifically for cathepsins D and E, and not for cathepsins B, H, or L. The cleavage of this substrate occurs at the Phe-Phe amide bond. It serves as a valuable tool for routine assays and mechanistic studies concerning cathepsins E and D.
- Fluorogenic substrate
- Specific for cathepsins D and E
- Does not act on cathepsins B, H, or L
- Cleavage at the Phe-Phe amide bond
- Suitable for routine assays
- Useful for mechanistic studies on cathepsins E and D
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Medchemexpress LLC D-Glucuronic acid (Standard) | 6556-12-3 | 25 G
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D-Glucuronic acid (Standard) is the analytical standard of D-Glucuronic acid, intended for research and analytical applications. It is a major component of many anti-inflammatory proteoglycans, which can promote embryonic development and inhibit cell aggregation. After being metabolized into ethyl glucuronide, D-Glucuronic acid activates Toll-like receptor 4 (TLR4), causing pain. D-Glucuronic acid and its derivative glucurono-lactone can serve as liver detoxifiers for human health prevention, and its derivatives also possess anti-tumor activity.
- Analytical standard for D-Glucuronic acid
- Intended for research and analytical applications
- Promotes embryonic development and inhibits cell aggregation
- Activates Toll-like receptor 4 (TLR4) when metabolized
- Serves as a liver detoxifier; derivatives possess anti-tumor activity
- Commonly used in HPLC, GC, and MS for research experiments
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Medchemexpress LLC Integrin alpha V beta 8 protein, mouse | ≥95.0% | 20UG
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Integrin alpha V beta 8 protein (mouse) is a recombinant heterodimer expressed in HEK293 cells with a C-terminal His tag, intended for research use in studies of integrin signaling, ligand binding, and cell adhesion. The product is supplied as a purified protein in defined sizes and is characterized by a reported purity and molecular weight range suitable for biochemical and cell-based assays.
- Recombinant mouse integrin heterodimer suitable for functional assays.
- Produced in HEK293 expression system to preserve mammalian modifications.
- His tag facilitates purification and detection in biochemical workflows.
- High purity supports reliable assay results (≥95.0%).
- Supplied in defined sizes for flexible experimental needs.
- Molecular weight consistent with alpha and beta subunits (80-140 kDa).
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Medchemexpress LLC Anti-Mouse Human Mac 10mg | 10mg
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Anti-Mouse/Human Mac-2/Galectin-3 Antibody (TIB-166) is a rat-derived anti-mouse/human Mac-2/Galectin-3 IgG2a monoclonal antibody Anti-Mouse/Human Mac-2/Galectin-3 Antibody (TIB-166) significantly inhibits IL-6 expression (inhibition rates 34 7% and 55 3%) Anti-Mouse/Human Mac-2/Galectin-3 Antibody (TIB-166) is often used for immunoprecipitation western blot immunofluorescence and flow cytometry[1][2][3][4]
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Medchemexpress LLC D-Dimannuronic acid sodium | 10 MG
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D-Dimannuronic acid sodium is an alginate extract derived from brown algae. This compound is primarily used in research to synthesize sulfated polymannuronate (SPMG)-derived oligosaccharides. It is intended for research use only.
- Derived from brown algae
- Used to synthesize sulfated polymannuronate (SPMG)-derived oligosaccharides
- For research use only
- Purity of 99.94%
- Molecular weight of 392.25
- Molecular formula is C12H17NaO13
- Appears as a white to off-white solid
- Soluble in H2O at 125 mg/mL (318.67 mM), requires ultrasonic treatment
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Medchemexpress LLC Prosaikogenin D | 103629-72-7 | 10 MG
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Prosaikogenin D is isolated from the roots of Buleurum bicaule Helm (Apiaceae) and exhibits anti-cancer activity.
- Suppresses the proliferation of A549 cells with an IC50 of 57.2 μg/mL.
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Medchemexpress LLC Integrin alpha 5 bet 50ug | 50ug
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ITGA5 is a multifunctional receptor that interacts with multiple ligands such as fibronectin fibrinogen PLA2G2A fibrillin-1 (FBN1) IL1B human metapneumovirus and soluble CD40LG ITGA5 recognizes RGD sequences and mediates cell adhesion through different binding sites Integrin alpha 5 beta 1 Protein Human (HEK293 His-Avi) is a recombinant protein dimer complex containing human-derived Integrin alpha 5 beta 1 protein expressed by HEK293 with C-Avi C-His labeled tag Integrin alpha 5 beta 1 Protein Human (HEK293 His-Avi) has molecular weight of 100-140 kDa
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Medchemexpress LLC IL-1RA/IL-1F3 Porci 500ug | 500ug
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IL-1RA/IL-1F3 proteins are powerful anti-inflammatory antagonists in the interleukin 1 family specifically targeting the pro-inflammatory cytokines IL1B and IL1A This protein counteracts the inflammatory effects of IL1 playing a critical role in preventing immune dysregulation and preventing uncontrolled systemic inflammation triggered by a variety of innate irritants including pathogens IL-1RA/IL-1F3 Protein Porcine is the recombinant Porcine-derived IL-1RA/IL-1F3 protein expressed by E coli with tag free
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Medchemexpress LLC 1-Acetylpiperazine-d4 | 1398065-90-1 | 132.20 | 25MG
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1-Acetylpiperazine-d4 is a deuterium-labeled form of 1-Acetylpiperazine. Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules, primarily as tracers for quantitation in drug development. Deuteration has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Deuterium labeled compound
- Suitable as a tracer for quantitation in drug development
- Potential to impact pharmacokinetic and metabolic profiles
- For research use only
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Apexbio Technology LLC Beta-Lipotropin (1-10), porcine 77875-68-4 25mg
Beta-Lipotropin 1-10 porcine is an endogenous opioid peptide fragment derived from the N-terminal region of beta-lipotropin It is structurally related to opioid peptides and interacts with opioid receptors to mediate morphine-like activity within the central nervous system Beta-Lipotropin 1-10 porcine exerts its biological effects through modulation of opioid receptor signaling pathways Based on these pharmacological properties Beta-Lipotropin 1-10 porcine holds research potential in neuropharmacological studies particularly in investigations related to endogenous pain modulation neurotransmission mechanisms and opioid receptor ligand interactions
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Medchemexpress LLC SAIKOSAPONIN D 25 mg
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SAIKOSAPONIN D 25MG
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